我组（18T7）对固态纳米孔改性与表征的研究进展进行了综述总结。纳米孔由于其可修饰性、可控性和敏感性等优点，近年来在生物分子测序、小分子检测、盐差发电、仿生物离子通道等领域大放异彩。在这些应用中，化学或生物修饰的作用是不可缺少的。与小分子相比，高分子的改性难度更大，方法也更多样。选择合适的修饰方法直接决定了研究的成功与否，因此，有必要对面向纳米孔的聚合物修饰方法进行总结。此外，研究过程中需提供明确的、令人信服的证据来证明纳米孔的改性是成功的，相应的表征方法也是必不可少的。因此，我们总结了聚合物改性纳米孔的方法和有效的表征方法。希望这篇综述能够为志同道合的研究者提供一些参考价值。

相关成果发表在《亚洲化学》Chemistry—An Asian Journal，第一作者是18T7组博士研究生逯文启，第二作者是大连理工大学本科生曹雨晨。以上研究工作得到国家自然科学基金项目、我所创新特区组启动基金、兴辽英才计划等项目的支持。

Recent advance in solid state nanopores modification and characterization

Wenqi Lu, Yuchen Cao, and Guangyan Qing*

Chem. - Asian J., 2022, 2200675.  DOI: 10.1002/asia.202200675.

Nanopore, due to its advantages of modifiable, controllability and sensitivity, has made a splash in recent years in the fields of biomolecular sequencing, small molecule detection, salt differential power generation, and biomimetic ion channels, etc. In these applications, the role of chemical or biological modification is indispensable. Compared with small molecules, the modification of polymers is more difficult and the methods are more diverse. Choosing appropriate modification method directly determines the success or not of the research, therefore, it is necessary to summarize the polymer modification methods toward nanopores. In addition, it is also important to provide clear and convincing evidence that the nanopore modification is successful, the corresponding characterization methods are also indispensable. Therefore, this review will summarize the methods of polymer modification of nanopores and efficient characterization methods. And we hope that this review will provide some reference value for like-minded researchers.